Signaling commitment
نویسندگان
چکیده
منابع مشابه
Signaling and transcriptional regulation in osteoblast commitment and differentiation.
The major event that triggers osteogenesis is the transition of mesenchymal stem cells into bone forming, differentiating osteoblast cells. Osteoblast differentiation is the primary component of bone formation, exemplified by the synthesis, deposition and mineralization of extracellular matrix. Although not well understood, osteoblast differentiation from mesenchymal stem cells is a well-orches...
متن کاملSmad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
Bone morphogenetic protein (BMP) signaling regulates embryonic hematopoiesis via receptor-mediated activation of downstream SMAD proteins, including SMAD1. In previous work, we showed that Smad1 expression is sufficient to enhance commitment of mesoderm to hemangioblast fate. We also found indirect evidence to support a subsequent repressive function for Smad1 in hematopoiesis. To test this hyp...
متن کاملCoordination of Fc receptor signaling regulates cellular commitment to phagocytosis.
During Fcγ receptor (FcR)-mediated phagocytosis by macrophages, cytoplasm advances over IgG-coated particles by the sequential ligation of FcR in plasma membranes. If FcR signaling was strictly autonomous, then the signals generated during phagocytosis should be proportional to the number of ligated receptors. By measuring FcR-dependent responses to beads coated with various densities of IgG, t...
متن کاملSimulating Terrorism: Credible Commitment, Costly Signaling, and Strategic Behavior
Wepresent two simulations designed to convey the strategic nature of terrorism and counterterrorism. The first is a simulated hostage crisis, designed primarily to illustrate the concepts of credible commitment and costly signaling.The second explores highlevel decision making of both a terrorist group and the state, and is designed to highlight scarce-resource allocation and organizational dyn...
متن کاملCommitment
A commitment scheme is a two-phase cryptographic protocol between two parties, a sender and a receiver, satisfying the following constraints. At the end of the Commit phase the sender is committed to a specific value (often a single bit) that he cannot change later on (Commitments are binding) and the receiver should have no information about the committed value, other than what he already knew...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2005
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem20111iti5